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This reduction limits the secretion of CXCL9, another key chemokine of the CXCL family, and CXCL10, thereby restricting effector T cell entry into tumor lesions and creating a T cell exclusion state that undermines the efficacy of PD-1/PD-L1 inhibitors

2025 Jun 28;56(4):210

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The expression of GIP receptors in vascular adipose tissue in endothelial cells and monocytes/macrophages probably influence each other and increase inflammation [16]

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