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In patients not taking an SGLT2 inhibitor (N = 2,983) the primary endpoint was reduced by 27% (HR 0.73

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Carbs-heavy dishes such as pizza and pasta are served in much smaller portions

2024 doi: 10.1172/jci.insight.174825

Conclusion Dietary modification personalized to individual preferences and treatment goals (e.g., caloric deficits of 500 kcal/day), combined with structured physical activity (e.g., 150 minutes of moderate-to-vigorous exercise per week), produces additive benefits beyond GLP-1 therapy alone, enhancing weight loss, improving body composition, and reducing visceral fat and inflammation

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