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This higher affinity can be attributed to its molecular design, which integrates GLP-1 activity into the GIP sequence [68]

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For help managing injection-related [side effects](/guides/retatrutide-side-effects-management-guide), see our companion guide

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Participants who took the 25 mg oral dose and stuck to the protocol lost an average of 1316.6% of their body weight over 64 weeks

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10.1016/j.neuron.2019.05.035 69 KincaidB.Bossy-WetzelE

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Luo G, Liu H, Lu H (2016) Glucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients

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