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If a patient continues to avoid nutritious foods (perhaps due to taste changes or trying to eat as little as possible), these deficiencies could persist or worsen

doi:10.1161/JAHA.125.041369

In SURMOUNT-1 (tirzepatide), about ~25% of the total weight lost was lean mass and ~75% was fat mass over 72 weeks (36)

Reporting negative or null findings prevents publication bias and aids meta-analysis across laboratories

While it is not a cure-all, and ongoing research is still uncovering the full scope of its effectiveness, many patients are now exploring regenerative medicine options to potentially aid in recovery from soft tissue injuries, joint issues, and other musculoskeletal concerns

Many struggle with fatigue, nausea, nutrient depletion, and eventual weight regain once therapy stops