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These stimulate intestinal L-cells through nutrient sensing and short-chain fatty acid production from bacterial fermentation

Hu W, Song R, Cheng R, et al

These results taken together suggest that adding even mild amounts of GR agonism (to increase energy expenditure) on top of a dual agonist like Tirzepatide is able to produce even more pronounced decreases in weight

Fitz-Patrick, J

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But supplemental psyllium has also been shown to help increase GLP-1 production, prolong feelings of fullness, and manage blood sugar