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In alzheimers disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: randomized, Placebo-Controlled, double-blind clinical trial

doi:10.1002/jnr.21483

has acted as consultant, advisory board member and speaker for Boehringer Ingelheim, Eli Lilly, Novo Nordisk and Sanofi, an advisory board member Lexicon, Pfizer, ShouTi Pharma Inc, AstraZeneca and Medtronic and as a speaker for AstraZeneca, Napp Pharmaceuticals, Novartis and Amgen

For example, niches may be created by addressing specific unmet needs in certain patient types (e.g., patients who prefer not to inject, or who failed prior lines of GLP-1s), or by addressing specific access issues (e.g., developing a lower-cost option, securing broader payer coverage)

Agents such as sitagliptin and saxagliptin are available for first-line or adjunctive therapy

doi: 10.1159/000330447 74 HegedsLShermanSITuttleRMvon ScholtenBJRasmussenSKarsblJDet al