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Gut Microbiota-Derived Tryptophan Metabolism Mediates Renal Fibrosis by Aryl Hydrocarbon Receptor Signaling Activation

5.4 Gastrointestinal Side Effects and Nutrient Loss Nausea and vomiting are well-documented adverse effects. Persistent vomiting or diarrhoea may: Increase electrolyte loss Reduce caloric intake Reduce dietary diversity However: These effects are typically transient and dose-related

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It is recommended to rotate application sites daily to avoid skin sensitivity

By activating its ubiquitously expressed receptor GLP1R, GLP-1 regulates multiple physiological processes which are summarized in Fig