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Three minutes after being placed in the box, they were presented with three tones (4kHz, 80 dB, 30 seconds), 60 seconds apart

For example, the largest STEP trial published to date reported that GI issues affected 74.2% of volunteers taking semaglutide, as opposed to 47.9% taking placebo
Canberra: Australian Government, Department of Health and Aged Care

The rate varies by individual based on genetics, diet, and activity level

K., Oldfield, B
