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The drugs compared: Zepbound List price: $1,060 per month for those paying out-of-pocket Active ingredient: Tirzepatide has also been marketed as an injectable Type 2 diabetes treatment (Mounjaro) since 2022

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Written By: Riya Bhilare BPharm Reviewed By: Pharmacally Editorial Team The landmark STEP UP trial has established a new milestone in obesity management, with semaglutide 7.2 mg delivering a first-time 21% average weight loss over 72 weeks, significantly outperforming the currently approved 2.4 mg dose and setting a new standard for pharmaceutical weight management interventions

The body mass index (BMI) is often used in epidemiological research to identify overweight and obesity, although it has limited sensitivity due to considerable inter-individual variability in the percentage of body fat, which is partially based on age, gender, and ethnicity