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In vitro, mouse pancreatic -cells (NIT-1 cells) were exposed to palmitic acid (PA), PA+exendin-4 (Ex-4), PA+GW, PA+GSK0660 (GSK, a PPAR antagonist), or PA+Ex-4+GSK

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Therefore, the aim of this study was to examine the anti-inflammatory, analgesic, and anti-degradative effects in OA using in vitro and in vivo experiments

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These drugs were developed to manage type 2 diabetes but they are used for

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Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted following nutrient intake, in response to elevated blood glucose levels, stimulating insulin secretion from pancreatic -cells and suppress glucagon secretion from pancreatic -cells

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Long-term semaglutide use for weight management shows generally favorable safety data in clinical trials, though individual outcomes depend on baseline health status, existing conditions, and genetic predispositions

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