reduce basal insulin dose when starting glp-1 receptor agonist Titration algorithm for Evolution of GLP‐1 Receptor Agonists
Description
Dual- and multi-receptor agonists may be a novel drug class to treat obesity and type 2 diabetes mellitus with high efficacy.

Clinical Significance: The 2025 updates reaffirm that while HbA1c remains central, a one-number-fits-all strategy is outdated

Most people taking a 1,250 version wont even know they need to tell their doctor
We also address current barriers to implementation and evidence-based use, ongoing clinical trials, and future directions, including combination therapies that may enhance efficacy and patient outcomes.
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GLP-1 receptor agonists (GLP-1 RAs) with exenatide b.i.d
