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Potential considerations with extended use include nutrient malabsorption and slightly increased infection susceptibility, though benefits often outweigh risks for those with persistent symptoms

With the pathways of CBD and autophagy in mind for neurodegeneration and metabolic disease, one is inspired to consider how these compare to the cellular pathways of recently improved FDA treatments for the treatment of glucose homeostasis and obesity in DM that can advocate future clinical utility for CBD

Magnsdttir et al., 2015)

Ro does not currently offer non-injectable GLP-1 options like oral tablets or lozenges, which some patients may prefer

GLP-1

Given similar side effect profiles and the convenience advantage of weekly versus daily dosing, semaglutide has largely superseded liraglutide as the preferred GLP-1 option for most patients