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This dual-target approach makes tirzepatide effective for managing diabetes and weight

Most published analyses rely on foreign unit costs and health system structures, while differing in assumptions regarding treatment duration, adherence, discontinuation, and post-treatment weight regain

Its called tirzepatide (Mounjaro)

I view lifestyle optimization as multiplying rather than adding to medication effects

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SURMOUNT-4 (Aronne et al., JAMA 2024) and a 2025 post-hoc analysis showed that cardiometabolic parameters that had improved on tirzepatide blood sugar, blood pressure, lipids, and weight largely reversed toward baseline after stopping, in proportion to the weight regained