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Clinical trials and observational data show that effective semaglutide therapy typically spans 12 to 24 months for meaningful weight loss plateaus

Nutrients, 14(15), 3169

The FLOW trial demonstrated meaningful reductions in kidney disease progression with semaglutide. The SELECT trial showed a 20% reduction in major adverse cardiovascular events in patients with obesity and established cardiovascular disease. These are not trivial findings

Mild to moderate nausea, temporary acid reflux, or temporary feelings of heavy stomach fullness

However when I received my FEDEX overnight Rx for Tirzepatide from Strive Pharmacy...Wow

So, if you want to take one of the newer GLP-1 medications like semaglutide or tirzepatide, you may be paying out of pocket for it