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Multivariate analysis showed no difference between placebo and liraglutide arms in HbA1c at 6 months (HbA1c:0.2mmol/mol, 11.3, 11.6, p=0.98) however, at 12 months HbA1c was significantly higher in the liraglutide arm (HbA1c:10.9mmol/mol, 1.1, 20.6, p=0.032)

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El glucagn acta aumentando los niveles de glucosa en sangre, en particular durante los periodos de ayuno, y contribuye a movilizar las reservas energticas.Los agonistas sintticos, como la semaglutida o la tirzetida, son pptidos estables que activan especficamente los receptores de estas hormonas, amplificando sus efectos beneficiosos sobre los niveles de azcar en sangre y el control del peso

We explore the underlying biological mechanisms, summarize clinical trial evidence, and highlight emerging applications in non-diabetic populations