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Adults with type 2 diabetes using semaglutide had a higher NAION incidence rate than when they were not using the medication, but adults newly prescribed semaglutide did not have a significantly increased risk for NAION compared with most other diabetes medications in a second analysis
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Atherosclerosis 237 , 140145 (2014)

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Long-term semaglutide users typically achieve 15% to 22% total body weight loss over 12 months with consistent use, compared to 2% to 4% with lifestyle modification alone
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