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Draw too little and you underdose

"On average, higher doses are associated with greater weight loss, but many patients achieve significant results with lower doses

By slowing the movement of food through the digestive system, tirzepatide can lead to gastric distension (stomach stretching) and increased pressure in the upper gastrointestinal tract

[2] When discontinuation is indicated, tapering by 50 mg every week minimizes rebound seizures or migraine exacerbation

This ritualistic aspect improves adherence because the injection becomes embedded in a calming evening routine rather than feeling like an interruption to a busy morning

Association without causality