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Insulin resistance adds an additional layer of vulnerability

Given the role of GLP-1RAs and other incretin-based medications widely used for the treatment of T2D and obesity, surprisingly little research has been directed at a comprehensive assessment of even the most frequent GI adverse events (125)

Its stepping in where the industrial model falls short: overpriced brand-name drugs, chronic shortages, rigid dose formulations, and one-size-fits-all products

These data suggest that semaglutide administered via the intestine is able to elicit a normal insulin response (Figure 7)

10.2337/dci18-0033 34 DavisJ.SinghS.SethiS.RoyS.MittraS.RayasamG.et al (2010)

Alcohol-based mouthwash dries out the tissues