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JCI Insight 8 , (2023)

Clin Exp Rheumatol

D.Russell-JonesD.et al

The interaction of GLP-1 and GLP-1RAs with GLP-1Rs of the brain includes various molecular and cellular mechanisms that are the basis for translation into the clinic, since these mechanisms counteract many key links in the pathogenesis of brain diseases

As such, INSL-5 may serve as an important link between the gut microbiota and host in the context of metabolism

Mechanisms of neuroprotection by estrogen
