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For example, someone who weighs 250 pounds burns more calories at rest than someone who weighs 200 pounds

Very salty foods draw moisture from oral tissues through osmosis, worsening the sensation of dryness

And its also the worst time to quit

These medications offer different pathways to appetite control and weight loss

During this time, your baseline metabolic rate may also shift downward slightly as you lose weight, requiring fewer calories to maintain your new body composition

For someone carrying enough weight to be facing serious metabolic risk such as type 2 diabetes, cardiovascular disease, joint failure etc, the trade-off likely makes sense