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Description
Incretins are defined as nutrient-stimulated gastrointestinal hormones that improve oral glucose tolerance by stimulating insulin secretion

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10.1111/j.1464-5491.2010.02938.x 28

Studies on subdiaphragmatic vagal deafferentation, which spares approximately 50% of vagal afferent nerves, have also confirmed the roles of vagal afferent nerves in mediating the effects of GLP-1 [30, 31], as confirmed in a mouse model with GLP-1R knockdown in vagal afferent nerves [32]

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This deceleration is normal
