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Weight loss was divided into three stages at both temperatures: 1) rapid initial weight loss, 2) slower gradual weight loss, and 3) weight maintenance

Semaglutide begins signaling appetite control within days, but meaningful appetite reduction typically emerges during weeks 2-4 of treatment as the medication accumulates in your system

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Clinical outcomes reflect these differences: **PPCOS II Trial Results**: - Live birth rate in PCOS: Letrozole 27.5% vs

Stopping GLP-1 medications like Wegovy often leads to significant weight regain within months