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Compared to placebo, patients receiving liraglutide had significantly greater weight loss after 6-month therapy [MD6.0 kg (95% CI,8.66 to3.33)

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We also describe the development of incretin-based pharmacotherapy, starting with exendin- 4 and ending with the identification of multi-incretin hormone receptor agonists, which appear to be the next major step in the fight against T2DM and obesity

GLP-1 receptor agonists, already used for Type 2 diabetes and obesity, show promise in reducing alcohol and drug-seeking behaviors through central reward and dopamine-related pathways