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He said its possible that acne flare-ups could be related to the short-term fluctuation in hormones, insulin sensitivity, and other factors as the body gets accustomed to the medications

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For example, fibroblast growth factor 21 (FGF21) exhibits important anti-inflammatory activity, and its deficiency can induce excessive KC death and accelerate the MASH-HCC transition [22]

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Mounjaro usually involves a tighter pathway and more prescribing oversight