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GLP-1 agonists give an average reduction of HbA1c of 11 mmol/mol in comparison with placebo (11) and SGLT2 inhibitors give an average HbA1c reduction of 7-9 mmol/mol (12)

While ED and testosterone deficiency were uncommon in younger men, non-diabetic men with obesity on semaglutide showed a higher risk

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Clinical trials also suggest that liraglutide may improve insulin sensitivity, but more research is needed [18]

The effects of GLP-1 receptor agonists on visceral fat and liver ectopic fat in an adult population with or without diabetes and nonalcoholic fatty liver disease: A systematic review and meta-analysis Real Science, Real Results Get expert insights on fueling your body, supporting metabolism, and living longerdelivered to your inbox every Monday