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As research has progressed, it has been revealed that vagal sensory neurons distributed in the intestinal and hepatic portal regions play a crucial role in sensing circulating GLP-1 and mediating its physiological actions

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10.1093/ntr/ntab066 63 YangY.HeL.HanS.YangN.LiuY.WangX.et al (2025)

Tirzepatide is the active ingredient in Zepbound, a GLP-1 receptor agonist
