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Reported Effects Glycemic control: As an adjunct to insulin, pramlintide produced a modest HbA1c reduction (on the order of a few tenths of a percentage point) versus placebo over 52 weeks in both type 1 and type 2 diabetes [3] [4]

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New results released this week from the SURMOUNT-5 clinical trial comparing tirzepatide (Zepbound) to semaglutide (Wegovy) are closely aligned to Truveta Researchs GLP-1 comparative effectiveness study, initially shared more than a year ago on November 27, 2023 and published earlier this year in JAMA Internal Medicine