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The rat model studies demonstrated positive and effective actions of GLP-1 molecules in the rat PA models, such as neurotrophic, neuroprotective, and anti-inflammatory effects on mitochondrial gene expression and neurogenesis, improvement in synaptic functions, reduction of neuron cells apoptosis, and decreased a-synuclein neuron deposition [9,49,52,54,55,57,58,59,60,61,62,63]

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Understanding whether you carry variants associated with stronger appetite suppression, faster satiety, or metabolic efficiency can support a more informed conversation about dosing, timing, and realistic expectations

Issa has served as a consultant and advisor for Eli Lilly and Company