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In male rats, hemangiomas of the mesenteric lymph node were increased significantly at 700 mg/kg/day or approximately 42 times the exposure from a 25 mg clinical dose
Reductions in total cholesterol and triglyceride levels in test subjects

Notice I said should

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The researchers asked participants: Are you currently taking or have you ever taken one of these drugs to lose weight or treat a chronic condition such as diabetes or heart disease?" Panel members were given three response options: (1) "Yes, I have taken them at least once"

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