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Mechanistic studies in humans have also examined acute effects on cardiac and vascular function, kidney physiology and neurohormonal pathways

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Lastly, when excluding BMI and pre-existing diabetes from the propensity score model, we observed similar findings to completely unadjusted estimates, for both semaglutide and liraglutide

Subject terms: Drug development, Type 2 diabetes, Type 2 diabetes Introduction Diabetes is a chronic metabolic disorder involving hyperglycemia and is characterized by defects in insulin secretion, insulin action, or both