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Lown, M., Fuller, R., Lightowler, H., Fraser, A., Gallagher, A., Stuart, B., Byrne, C., & Lewith, G

Currently, there are no known direct pharmacological interactions between GLP-1 receptor agonists and over-the-counter digestive enzyme supplements reported in the medical literature or FDA prescribing information, though evidence is limited

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In particular, the multiple metabolic actions of glucagon highlight the importance of understanding the contributions of individual hormone action to inform the safe, effective and tailored use of GLP-1/glucagon co-agonists to target weight loss and metabolic disease in the future

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