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CB1 is widely expressed in the central nervous system (CNS) and brain, but is also expressed in peripheral tissues such as adipose tissue, skeletal muscle, and in the liver, kidney, gut and pancreas

One of the most critical lifestyle changes you can make is adjusting your diet, which will significantly impact the sustainability of your weight loss while on the medication and once you discontinue medication and also mitigate side effects when you are on the medication

Before and after treatment, a kidney biopsy is obtained for single-cell sequencing, and multiparametric kidney MRI is performed

In studies, participants achieved reductions in HbA1c levels, indicating better blood glucose management

For many people, the biggest advantage is accessibility

There is no built-in lifestyle-coaching program or app-based progress tracking