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In 2019, 7.1% of the adult population of Great Britain used e-cigarettes [6] and in the European Union (EU), the use of e-cigarettes increased from 7.2% in 2012 to 11.6% in 2014 [23]

19 Strengths and limitations This study used a double-blind, placebo-controlled, four-way, crossover design with recreational users to investigate actual and estimated dose of cannabis and tobacco in a joint