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However, evidence that ADHD symptoms improve with nicotine administration among nonsmokers suggests that there may be theoretical potential for a combined therapeutic effect for nicotine dependence and ADHD.[21,22] Bupropion is another effective smoking cessation treatment.[45,46] It has additionally shown efficacy in treating ADHD,[47] but has only been specifically investigated for smoking cessation in individuals with ADHD in one pilot study.[48] Further research is needed to determine whether bupropion can effectively treat both conditions simultaneously