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For example, from the main trading nations of Western Europe, it was much easier to sail westwards after first going south of 30 N latitude and reaching the so-called trade winds, thus arriving in the Caribbean rather than going straight west to the North American mainland

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15,20 Consistent marijuana use can create chronic inflammation of the oral epithelium and leukoplakia, increase the risk of periodontal diseases and delay wound healing

Smokers are 2 to 4 times more likely to develop heart disease

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