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Hoffmann D, Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke

Smoking rates briefly rose in some of the first few years after the Surgeon General report's release, as the tobacco industry ramped up advertising to women and minorities, says Mark Pertschuk, a long-time anti-tobacco activist and director of the advocacy group Grassroots Change

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Substance abuse , where individuals who struggle with addiction to other substances like alcohol or drugs are at a higher risk for nicotine dependence