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A 40-year-old American man in 2014 could expect to live nearly eight years longer than his 1964 counterpart, and roughly a third of that improvement comes from tobacco control alone

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High carbon load + sustained 24/7 operation is the mechanism

Nevertheless, trends in such biases are unlikely to change markedly over time (see Supplementary File) and thus they are unlikely to substantially impact on observed trends in RRs and RDs over time

Source: Journal of the American College of Cardiology 3