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Moreover, siRNA-mediated NLRP3 gene silencing decreased both NLRP3 and caspase-1 levels while restoring cell viability

COPD is a heterogeneous condition, with between-individual variation in the nature and severity of airway inflammation [42] and the inflammatory cell profile also varies in large and small airways and with severity of COPD, hence careful appraisal is needed [43]

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