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Collagen IV, a major component of the basement membrane produced by both keratinocytes and fibroblasts, is also reduced in quantity with skin aging 48,49

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Keep in mind that smoking is a leading cause of death and that the effects of secondhand smoke can be fatal

A systematic review and meta-analysis of 26 longitudinal studies found that stopping smoking was also associated with long-term improvements in mental health similar in effect size to taking anti-depressants, and the benefit was at least as large in people with psychiatric conditions (Taylor et al ., 2014)

Early awareness and timely medical care can prevent serious neurological complications

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