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However, such prolonged nicotine treatment significantly attenuated the magnitude of cisplatin-mediated apoptosis to about two-fold reduction

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Front Neurol

Russell (1996) noted that nicotine keeps people smoking the cigarettes that kill so many, but it is combustion and pyrolysis the heating of organic material that generate the tars and other toxins responsible for smoking-related morbidity and mortality, not the nicotine itself

PMC 535959