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The Lancet editorial notes Public Health England used the guesstimate despite it being based on the opinions of a small group of individuals with no prespecified expertise in tobacco control and an almost total absence of evidence

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When you inhale smoke, it irritates tissues and cells in your respiratory system, sometimes causing pharyngitis, the medical term for a sore throat

As a matter of fact, Winters and Difranza reported having received hundreds of phone calls from smokers who quit on learning about alpha radiation in cigarette smoke, after the publication of a letter denouncing the lack of research on 210 Po in tobacco in The New England Journal of Medicine 2,7,20