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In its letter the FDA also cited several unapproved claims that Puff Bars e-cigarettes present a lower risk of tobacco-related disease or are less harmful than traditional cigarettes

Most smoking attributable fractions will be zero in that smoking is not implicated in any way for that underlying cause of death, but deaths with an underlying cause for a smoking-related condition (such as lung cancer or COPD) will have a smoking attributable fraction higher than zero and that fraction is likely to differ for men and women, and for different age groups

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