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In other words, nicotine has become drastically more accessible, and most of the disposables driving these numbers were never actually authorized for sale in the first place

As a result, these tissues would have fewer receptors for said alarms (such as IFN) and would exhibit a slower response to infection (like delayed infection cytokine responses), resulting in worse disease outcomes

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doi: 10.1136/bmjopen-2021-057360 20

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