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8 In a 2016 Cochrane Review citing evidence from two randomized controlled trials totaling 662 participants, those using nicotine-containing e-cigarettes were more likely to achieve six months of abstinence from conventional cigarettes compared with those assigned to non-nicotine-containing e-cigarettes (risk ratio 2.29, 95% CI 1.054.96)

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Also significant during the 1920s was that the advertising industry grew and expanded alongside the huge increase of cigarette sales

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