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21 22 This process is at least partially an autologous effect, with other cells such as bronchial epithelial cells shown to release increased IL-8 in response to CS that would contribute to stimulate macrophage and neutrophil influx

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There are those who showed increased neutrophilic inflammation, NET generation, and inflammatory response, while others showed the exact opposite (Table 1)

The rationale for the final model is that BMI and health status may be affected by tobacco status, but these covariates also adjust for other differences that may be correlated with tobacco use and with mortality (i.e., relevant confounders)

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