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Lecithin-like adhesion glycoproteins, so called selectins, mediate in movement of leukocytes, while firm adhesion and subsequent trans-endothelium migration of leukocytesis mediated by interaction of integrin (CD11/CD18, VLA-4) situated on leukocytes and immunoglobulin-like adhesion molecules on endothelium cells (ICAM-1, VCAM-1) (30)