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During the study, researchers measured hormone levels before the women quit smoking and at 6, 12, 24, and 48 weeks after quitting

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The researchers hypothesized that the low-nicotine cigarettes would be perceived by smokers as less risky and would be rated as less desirable than normal-nicotine-content cigarettes

For acute 5-HT 1A R antagonist studies, rats were given a single infusion of WAY-100,635 (100 g/kg, i.v.), L-741,626 (2 mg/kg, i.p.), or vehicle 20 min prior to self-administration testing