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In modern Africa, smoking is, in most areas, considered an expression of modernity, and many of the strong adverse opinions that prevail in the West receive less attention

In 1964, a landmark report on smoking tobacco was published by the United States' Surgeon General

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Epinephrine and norepinephrine can cause the smooth muscles in certain blood vessels to contract, narrowing the opening and reducing the space through which blood can flow

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Many studies have reported that chronic smoking is a risk factor for increased arterial stiffness, however, a number of investigations have not found differences in arterial stiffness between smokers and never smokers 22,23