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LITERATURE REVIEW 1) Cigarette smoking effects on the respiratory epithelium The epithelium coating the upper respiratory tract acts as a first line of defense against invasive agents (pollutants, allergens, microorganisms), and it can cause upper airway symptoms and diseases when in contact with these agents.5 Inhaled cigarette smoke, both passively as well as actively, has been associated with chronic irritation and discomfort on the eyes, nose and oropharynx.6 Since 1964, when a report was published about smoking by the U.S

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Compared to cigarettes, they highlight that it tastes better, they get more effect with less quantity, and it is ultimately cheaper 7 , more discreet, allowing for less socially stigmatized use 8,9
The findings, published in the American Journal of Physiology, show e-cigs and refills are not well regulated and their long-term effects on health are unknown

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E., Turner, J
