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Our study shows that nicotine binds to the enzyme responsible for the synthesis of estrogen in the thalamus the brain region with the highest expression of this enzyme and of receptors for nicotine. Comasco said her team was surprised by how powerful nicotine was on areas of the brain targeted by addictive substances and added that they arent yet sure what the behavioral or cognitive outcomes are

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Side effects such as nausea, sleep disturbances, and, in some rare cases, mood changes can dampen its appeal. In addition, the cost factor cannot be ignored

In addition, the rise of vaping and e-cigarettes has introduced a non-combustible nicotine alternative that appeals to smokers seeking a less harmful option, further drawing consumers away from traditional tobacco products, including clove cigarettes